Cosfroviximab (Biosimilar Reference Antibody) (Zaire Ebolavirus Glycoprotein)
Cosfroviximab (Biosimilar Reference Antibody) (Zaire Ebolavirus Glycoprotein)-RA0822-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.
Cosfroviximab (Biosimilar Reference Antibody) (Zaire Ebolavirus Glycoprotein)

Catalog: 

RA0822

Target

Zaire Ebolavirus Glycoprotein

Isotype

IgG1 - kappa

Applications

Functional Assays

Reactivities

Virus

Size (＄)：

100 μg-50;1 mg-210;5 mg-500;10 mg-800;25 mg-1750;50 mg-3000;100 mg-4600

Data Sheet

Material Safety Data Sheet

Certificate of Analysis

Product Description

Cosfroviximab (c13C6-FR1) is an investigational chimeric (mouse/human) monoclonal antibody developed for research and potential therapeutic use against Ebola virus disease (EVD). It belongs to a class of biologics designed for passive immunotherapy, aiming to neutralize the virus and provide immediate, short-term protection or treatment. Its development is part of the broader effort to create effective antibody-based countermeasures against this highly lethal pathogen.

Synonyms

c13C6-FR1-N

CAS

1792982-57-0

Isotype

IgG1 - kappa

Host

Chimeric

Target

Zaire Ebolavirus Glycoprotein

Reactivity

Virus

Expression System

CHO

Applications

Functional Assays;

Purity

>98% by SDS-PAGE

Concentration

Bottled at the concentration indicated on the vial.

Buffer

0.01M PBS, pH 7.4, contains no stabilizers or preservatives.

Endotoxin

<1.0 EU/mg as determined by LAL method

Conjugation

Non-conjugated

Formulation

Liquid or Lyophilized powder Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Storage

store at -20°C or -80°C. Avoid repeated freeze.

Type

Antibody

Purposes

For research use only

References 1

Carly Fleagle Chisholm, et al. Thermostable Ebola virus vaccine formulations lyophilized in the presence of aluminum hydroxide. Eur J Pharm Biopharm. 2019 Mar;136:213-220.

References 2

References 3

References 4

References 5

Product Citations 1

Product Citations 2

https://pubmed.ncbi.nlm.nih.gov/30703544/

Target Description

Synonyms

EBOV

Biology Area

Innate Immunity;Immunology

Function

Ebola virus glycoprotein (EBOV-GP), specifically the envelope glycoprotein expressed on the surface of the Ebola virus. EBOV-GP is essential for viral attachment, fusion, and entry into host cells. The antibody is engineered to bind with high affinity to a specific epitope on EBOV-GP.

Additional Articles 1

Additional Articles 2

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