Grisnilimab (Biosimilar Reference Antibody) (CD7)
Grisnilimab (Biosimilar Reference Antibody) (CD7)
Grisnilimab (Biosimilar Reference Antibody) (CD7)-RA0128-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.
ELISA plate pre-coated Antigen protein, can bind Grisnilimab (Biosimilar Reference Antibody) (CD7)-RA0128 in a linear range of 3.91–31 ng/mL.
Grisnilimab (Biosimilar Reference Antibody) (CD7)

Catalog: 

RA0128

Target

CD7

Isotype

IgG2a - lambda

Applications

ELISA;FC;Functional Assays;IF

Reactivities

Human

Size (＄)：

100 μg-50;1 mg-210;5 mg-500;10 mg-800;25 mg-1750;50 mg-3000;100 mg-4600

Data Sheet

Material Safety Data Sheet

Certificate of Analysis

Product Description

Grisnilimab is an investigational immunoglobulin G2a (IgG2a) monoclonal antibody targeting CD7. It is classified as an anti-CD7 monoclonal antibody and is associated with research into Wilms' tumor (WT1), a pediatric kidney cancer. The designation "(WT1)" likely refers to the Wilms' tumor 1 gene/protein context of its study, not its direct target.

Synonyms

WT1

CAS

2367001-70-3

Isotype

IgG2a - lambda

Host

Murine

Target

CD7

Reactivity

Human

Expression System

CHO

Applications

ELISA, FC, Functional Assays, IF; Recommended dilution: FC, IF:1:200

Purity

>98% by SDS-PAGE

Concentration

Bottled at the concentration indicated on the vial.

Buffer

0.01M PBS, pH 7.4, contains no stabilizers or preservatives.

Endotoxin

<1.0 EU/mg as determined by LAL method

Conjugation

Non-conjugated

Formulation

Liquid or Lyophilized powder Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Storage

store at -20°C or -80°C. Avoid repeated freeze.

Type

Antibody

Purposes

For research use only

References 1

Scharnhorst V, et al. WT1 proteins: functions in growth and differentiation. Gene. 2001 Aug 8;273(2):141-61.

References 2

Hertler AA, et al. An immunotoxin for the treatment of T-acute lymphoblastic leukemic meningitis: studies in rhesus monkeys. Cancer Immunol Immunother. 1989;28(1):59-66.

References 3

References 4

References 5

Product Citations 1

Product Citations 2

https://pubmed.ncbi.nlm.nih.gov/11595161/
https://pubmed.ncbi.nlm.nih.gov/2783301/
https://www.oursmab.com/News/the-target-of-cellular-immunotherapy-CD7.html

Target Description

Synonyms

CD7 antigen (p41), GP40, LEU-9, TP41, Tp40

Biology Area

Immunology;CD Markers

Function

CD7, a transmembrane glycoprotein belonging to the immunoglobulin superfamily. CD7 is primarily known as a cell surface antigen expressed on T cells and natural killer (NK) cells, and it is also found on some myeloid progenitors and subsets of leukemic cells (e.g., in T-cell acute lymphoblastic leukemia). Its precise physiological function is not fully defined but is involved in T-cell activation and adhesion.

Additional Articles 1

the-target-of-cellular-immunotherapy-CD7

Additional Articles 2

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