Gulgafafusp (Biosimilar Reference Antibody) (GLP1R)
Gulgafafusp (Biosimilar Reference Antibody) (GLP1R)
Gulgafafusp (Biosimilar Reference Antibody) (GLP1R)-RA0275-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.
ELISA plate pre-coated Antigen protein, can bind Gulgafafusp (Biosimilar Reference Antibody) (GLP1R)-RA0275 in a linear range of 3.91–31 ng/mL.
Gulgafafusp (Biosimilar Reference Antibody) (GLP1R)

Catalog: 

RA0275

Target

GLP1R

Isotype

IgG2 - kappa

Applications

ELISA;FC;Functional Assays;IF

Reactivities

Human

Size (＄)：

100 μg-50;1 mg-210;5 mg-500;10 mg-800;25 mg-1750;50 mg-3000;100 mg-4600

Data Sheet

Material Safety Data Sheet

Certificate of Analysis

Product Description

Gulgafafusp alfa is an investigational, human immunoglobulin G2 kappa (IgG2κ) monoclonal antibody being developed for the treatment of metabolic diseases, particularly type 2 diabetes (T2D) and potentially obesity. It represents a novel biologic approach by targeting the glucagon-like peptide 1 receptor (GLP1R).

Synonyms

CAS

2642374-02-3

Isotype

IgG2 - kappa

Host

Humanized

Target

GLP1R

Reactivity

Human

Expression System

CHO

Applications

ELISA, FC, Functional Assays, IF; Recommended dilution: FC, IF:1:200

Purity

>98% by SDS-PAGE

Concentration

Bottled at the concentration indicated on the vial.

Buffer

0.01M PBS, pH 7.4, contains no stabilizers or preservatives.

Endotoxin

<1.0 EU/mg as determined by LAL method

Conjugation

Non-conjugated

Formulation

Liquid or Lyophilized powder Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Storage

store at -20°C or -80°C. Avoid repeated freeze.

Type

Antibody

Purposes

For research use only

References 1

IMGT

References 2

References 3

References 4

References 5

Product Citations 1

Product Citations 2

https://www.imgt.org/mAb-DB/mAbcard?AbId=1448
https://www.oursmab.com/News/Treatment-of-obesity-and-metabolic-diseases-target-GLP1R.html

Target Description

Synonyms

glucagon-like peptide 1 receptor

Biology Area

Metabolism

Function

GLP1R is a multifaceted receptor critical for metabolic and cardiovascular health. Its pharmacologic activation has revolutionized type 2 diabetes and obesity treatment, with ongoing expansion into cardiorenal and neurological diseases. Innovations in drug design continue to enhance efficacy, tolerability, and patient access.

Additional Articles 1

Treatment-of-obesity-and-metabolic-diseases-target-GLP1R

Additional Articles 2

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