Tarcocimab (Biosimilar Reference Antibody) (VEGFA)
Tarcocimab (Biosimilar Reference Antibody) (VEGFA)
Tarcocimab (Biosimilar Reference Antibody) (VEGFA)-RA0811-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.
ELISA plate pre-coated Antigen protein, can bind Tarcocimab (Biosimilar Reference Antibody) (VEGFA)-RA0811 in a linear range of 3.91-125 ng/mL.
Tarcocimab (Biosimilar Reference Antibody) (VEGFA)

Catalog: 

RA0811

Target

VEGFA

Isotype

IgG1 - kappa

Applications

ELISA;FC;Functional Assays;IF

Reactivities

Human

Size (＄)：

100 μg-50;1 mg-210;5 mg-500;10 mg-800;25 mg-1750;50 mg-3000;100 mg-4600

Data Sheet

Material Safety Data Sheet

Certificate of Analysis

Product Description

Tarcocimab is a humanized monoclonal antibody targeting vascular endothelial growth factor A (VEGF-A). It binds to VEGF-A to inhibit its interaction with VEGF receptors (VEGFR-1 and VEGFR-2), suppressing angiogenesis and vascular leakage. It is being developed for the treatment of neovascular age-related macular degeneration (nAMD) and other retinal vascular diseases.

Synonyms

OG1953

CAS

2408661-40-3

Isotype

IgG1 - kappa

Host

Humanised

Target

VEGFA

Reactivity

Human

Expression System

CHO

Applications

ELISA, FC, Functional Assays, IF; Recommended dilution: FC, IF:1:200

Purity

>98% by SDS-PAGE

Concentration

Bottled at the concentration indicated on the vial.

Buffer

0.01M PBS, pH 7.4, contains no stabilizers or preservatives.

Endotoxin

<1.0 EU/mg as determined by LAL method

Conjugation

Non-conjugated

Formulation

Liquid or Lyophilized powder Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Storage

store at -20°C or -80°C. Avoid repeated freeze.

Type

Antibody

Purposes

For research use only

References 1

IMGT

References 2

References 3

References 4

References 5

Product Citations 1

Product Citations 2

https://www.imgt.org/mAb-DB/mAbcard?AbId=1188
https://www.oursmab.com/News/The-angiogenin-VEGFA.html

Target Description

Synonyms

vascular endothelial growth factor A, VEGF-A, VEGF

Biology Area

Ophthalmology;Cancer Biology

Function

Vascular endothelial growth factor-A (VEGF-A), a key signaling protein that promotes the growth of abnormal, leaky blood vessels in the eye. These vessels are responsible for vision loss in conditions like wet AMD. As a VEGF inhibitor, Brolucizumab functions

Additional Articles 1

The-angiogenin-VEGFA

Additional Articles 2

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